Program & Speakers

Thursday, November 27^th | Day 1

8.00 am - 9.00 am Registration

9.00 am - 9.30 am Welcome Ceremony

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9.30 am - 10.50 am Session 1: Refinement 

(Chair: René Tolba, Aachen)

Patrick Reinhardt (Bochum) - Refining operant behavioral assessment in an open-science homecage environment

Esther Mahabir-Brenner (Cologne) - Managing old-aged mice

Agnesa Mazrekaj (Duesseldorf) - Refinement in aortic research

Florian Alexander Dehmelt (Tuebingen) - Electrical stunning as a way to kill zebrafish? Behavioural and neurophysiological effects observed in larvae

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10.50 am - 11.10 am Coffee Break

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11.15 am - 1.00 pm Session 2: New Thinking in 3Rs 

(Chair: Sabine Bischoff, Duesseldorf)

Julia Menon (Utrecht) -  Does Preregistration Work? Evidence from the First Evaluation in Animal Research

Daniel Hoffmann (Essen) - Reduction of animal numbers by computational analyses that maximize information gain per animal

Emma Pietsch (Berlin) - From 3R to 6R – Building Trust in Preclinical Models through Quality and Transparency

Speaker from participants - Presentation of results from Pre-conference Satellite Workshop for Early Career Researcher (November, 26th)

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1.00 pm - 2.00 pm Lunch Break

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2.00 pm - 2.40 pm Session 3: Short talks

(Chair: Christine Hartmann, Muenster)

Short talks from selected abstracts

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2.45 pm - 3.30 pm Session 4: Panel

(Chair: Valeska Stephan, Rostock, Nicole Linklater, Marburg)

Ask the experts ?! - interactive Q&A session

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3.30 pm - 4.30 pm Poster Session (odd numbers) & Coffee Break

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4.30 pm - 5.40 pm Session 5: Replacement 

(Chair: Marieta Toma, Bonn)

Joana Witt (Düsseldorf) -  3D Tissue Models of the Ocular Surface and Beyond

Yotam Menuchin-Lasowski (Muenster) - Developing an iPSC-Derived Optic Nerve Model for the Study of Myelin Diseases

Ivonne Vazquez (Bonn) - Generation of Vascularized Lung Organoids for Disease Modelling

Egor Dzyubenko (Essen) - Maturation and Vascularization of Human Brain Organoids for Next-Generation Preclinical Stroke Models

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5.40 pm - 5.50 pm Wrap-up Day 1

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From 7.30 pm and on Get-Together at CT² in Aachen, Germany
 

Friday, November 28^th | Day 2

8.30 am - 9.00 am Registration

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9.00 am - 10.30 am Session 6: Keynote Lecture 

(Chair: Philip Dammann, Essen)

Chris Barkus (London) - NC3Rs - From Innovation to Implementation: 20 Years of Supporting the 3Rs to Pioneer Better Science

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10.30 am - 11.40 am Poster Session (even numbers) & Coffee Break

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11.40 am - 1.00 pm Session 7: Reduction 

(Chair: Branko Zevnik, Cologne)

Nicole Schupp (Duesseldorf) - Use of 3R-compliant methods to investigate nephro- and hepatotoxicity

Roland Ullrich (Cologne) -  Lymphoma-associated myeloid-monocytic (LAMM) cells mediate resistance against CAR-T cell therapy in aggressive B-cell lymphoma 

Oliver Dräger (Bielefeld) - Establishment of a Human iPSC-Derived Nociceptive Neuron Model for the Investigation of Sex-specific Differences in Migraine Pathophysiology

Ralf Weiskirchen (Aachen) - From Bile Duct Ligation and Carbon Tetrachloride-Induced Liver Injury to Biochips: The Evolving Toolbox of Experimental Liver Models

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1.00 pm - 1.15 pm Wrap-up and Closing Remarks

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1.30 pm - 3.00 pm 3R-Network Meeting for 3R-Centers                                     (invitation only)